The Lazzara Lab studies fundamental and applied aspects
of mammalian cell signaling and receptor trafficking.
Signaling regulation by the epidermal growth factor receptor (EGFR), protein tyrosine phosphatase SHP2, and multipurpose protein Sprouty2, and the impact on cancer response to targeted therapies, have been areas of recent interest. The lab also studies receptor-mediated processes in renal physiology that maintain the normal glomerular filtration barrier and enable the reabsorption of filtered proteins from the proximal tubule. A combination of experimentation and computational modeling approaches (mechanistic and data-driven) are employed to study these problems.
The Lazzara Lab seeks enthusiastic applicants to fill
open positions for postdoctoral research associates,
graduate research assistants, laboratory technical staff,
and undergraduate researchers with a start date of August
1, 2016 or later. Candidates should send a current c.v. to